Details of Research Outputs

TitleDiscovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo
Author (Name in English or Pinyin)
Luo, G.1; Li, Z.1; Lin, X.1; Li, X.2; Chen, Y.3; Xi, K.2; Xiao, M.1; Wei, H.1; Zhu, L.2; Xiang, H.1
Date Issued2020-11-06
Source PublicationActa Pharmaceutica Sinica B
ISSN22113835
DOI10.1016/j.apsb.2020.11.001
Firstlevel Discipline生物学
Education discipline科技类
Published range国外学术期刊
References
[1] Virani, S.S., Alonso, A., Benjamin, E.J., Benjamin, E.J., Bittencourt, M.S., Callaway, C.W., et al. Heart disease and stroke statistics-2020 update: a report from the american heart association. Circulation 141 (2020), e139–e596.
Citation statistics
Cited Times:43[WOS]   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
Identifierhttps://irepository.cuhk.edu.cn/handle/3EPUXD0A/1820
CollectionSchool of Science and Engineering
Arieh Warshel Institute for Computational Biology
School of Medicine
Corresponding AuthorZhu, L.; Xiang, H.
Affiliation
1.State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, China
2.School of Life and Health Sciences and Warshel Institute for Computational Biology, The Chinese University of Hong Kong, Shenzhen, 518172, China
3.Key Laboratory of Smart Drug Delivery, Ministry of Education School of Pharmacy, Fudan University, Shanghai, 201203, China
Corresponding Author AffilicationSchool of Medicine
Recommended Citation
GB/T 7714
Luo, G.,Li, Z.,Lin, X.et al. Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo[J]. Acta Pharmaceutica Sinica B,2020.
APA Luo, G., Li, Z., Lin, X., Li, X., Chen, Y., .. & Xiang, H. (2020). Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo. Acta Pharmaceutica Sinica B.
MLA Luo, G.,et al."Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo".Acta Pharmaceutica Sinica B (2020).
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